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Can Metformin Work With Irregular Cycles

There is inadequate evidence to make a recommendation about the use of metformin for irregular menstrual cycles. Any efficacy in regularising menstruation usually takes at least 5 months. Weight loss has proved more efficient than metformin in restoring menstrual regularity.

The latest PCOS guidelines make the following recommendations regarding the use of metformin for non-conceptional indications:

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